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Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. For treatment of acute attacks of malaria in adults, four tablets are usually taken right away, followed by two tablets 6 to 8 hours later and then two tablets on each of the next 2 days.

For prevention or treatment of malaria in infants and children, the amount of hydroxychloroquine is based on the child's weight. Your doctor will calculate this amount and tell you how much hydroxychloroquine your child should receive. For lupus erythematosus, one or two tablets are usually taken once or twice daily.

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For rheumatoid arthritis, one to three tablets are usually taken once a day. Hydroxychloroquine can be taken with a glass of milk or a meal to decrease nausea. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydroxychloroquine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you, do not stop taking hydroxychloroquine without talking to your doctor. Symptoms of rheumatoid arthritis will return if you stop taking hydroxychloroquine. Hydroxychloroquine is used occasionally to treat porphyria cutanea tarda.

Talk to your doctor about the possible risks of using this drug for your condition. Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem.

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Less than one person in 5, develops the problem. Only an eye doctor can see if you have a problem with your retina. Almost always the damage will go away if it is found early and the medicine stopped.

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You should not take this medicine if you already have problems with the retinas in your eyes. You should not take this if you have an allergy to antimalarial medications. Read our easy-to-print PDF version of this fact sheet. Please note: This information is intended to complement, not replace, the advice and care you receive from medical and health professionals. For over a century, a leader in patient care, medical education and research, with expertise in virtually every specialty of medicine and surgery.

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This can happen in individuals with a condition known as G6PD deficiency or porphyria. In rare cases, hydroxychloroquine can cause visual changes or loss of vision.

Such vision problems are more likely to occur in individuals taking high doses for many years, individuals 60 years or older, or those with significant kidney disease. At the recommended dose, development of visual problems due to the medication is rare. It is recommended that you have an eye exam within the first year of use, then repeat every one to five years based on current guidelines. Although there are few drug interactions with hydroxychloroquine, to be safe be sure to tell your doctor about all of the medications you are taking, including over-the-counter drugs and natural remedies.

This information is provided for general education only. Individuals should consult a qualified health care provider for professional medical advice, diagnosis and treatment of a medical or health condition.

Do you need help? Call Help Get more information. How to Take It Hydroxychloroquine comes in an oral tablet.