Despite the fact that most COVID cases and mortalities were reported in China, the WHO has declared this outbreak as the sixth public health emergency of international concern.
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Adults represent the population with the highest infection rate; however, neonates, children, and elderly patients can also be infected by SARS-CoV In addition, nosocomial infection of hospitalized patients and healthcare workers, and viral transmission from asymptomatic carriers are possible. The most common finding on chest imaging among patients with pneumonia was ground-glass opacity with bilateral involvement.
Severe cases are more likely to be older patients with underlying comorbidities compared to mild cases. To date, effective treatment is lacking; however, clinical trials investigating the efficacy of several agents, including remdesivir and chloroquine, are underway in China. New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID?
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Despite drastic containment measures, the spread of this virus is ongoing. The efforts of international health authorities have since focused on rapid diagnosis and isolation of patients as well as the search for therapies able to counter the most severe effects of the disease. Preliminary trials of chloroquine repurposing in the treatment of COVID in China have been encouraging, leading to several new trials. Juurlink said a vaccine is a year or 18 months away but that data gathered worldwide could point to safe and effective treatments within a month or two.
We will look back a year from now and marvel at how much was done in such a short time, but we are just at the beginning of it all. The key right now is preventing and slowing the spread of the virus to give researchers and clinicians the time to develop treatments to minimize symptoms and get people out of hospital faster.
Chloroquine hype fuelled by Trump in fight against COVID-19 is 'dangerous': Canadian doctor
Drug-maker Novartis has vowed to donate up to million doses of hydroxychloroquine to support the global pandemic response. Teva Pharmaceutical Industries said it plans to donate more than 10 million tablets of hydroxychloroquine to hospitals in the U. Bayer also said it would donate three million tablets of its chloroquine phosphate drug, sold under the name Resochin. Concerned about a run on the drugs amid shortages reported in the U.
For those living with lupus, a chronic autoimmune disease, hydroxychloroquine is proven to reduce mortality by 50 per cent, prevent disease flares and cardiovascular complications, and reduce the need for hospitalization, according to a press release from Lupus Canada. More coronavirus coverage Interactive. Coronavirus in Canada. Map: Tracking the spread around the world. Facts Vs. Who is most at risk of dying from coronavirus?
Fearing coronavirus, Arizona man dies after taking a form of chloroquine used in aquariums - CNN
Cases in Canada Interactive. Quebec 'an army of 8. But the things you have to watch out for with chloroquine are cardiac side effects. It can cause [heart] arrhythmias, especially in people with a history of cardiac disease.
Arizona Man Dies From Chloroquine Overdose After Listening to Trump Coronavirus Press Conference
So I do worry that if people are using this willy-nilly in older patients with cardiac history that we could run into trouble. Also, for people with a lot of melanin in their skin YL: How optimistic are you about the potential for this to treat COVID, and is it possible that the positive results shown in this early study may not be replicated? CP: It's a good drug that has saved a lot of lives. The question is whether it gets efficacious and whether it's safe for this use in these patients. Those are really important questions that — until you've done a randomized controlled trial — you're just not going to have the evidence.
The history of medical treatments is just rife with examples of things where there was a biologically plausible reason to believe the drug would work So when Dr.
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Fauci says we need to expeditiously to do randomized clinical trials and find out is it safe He's absolutely right. There's no other way to have any degree of confidence that it's working.
So, it's reasonable to be hopeful, but that's not a reason to start using it. CP: Nobody should be stocking up I don't think we have the evidence for that.
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An individual physician is always in a position to make a decision For the latest news on the evolving coronavirus outbreak, follow along here. According to experts, people over 60 and those who are immunocompromised continue to be the most at risk. Read more from Yahoo Lifestyle. Confused about the coronavirus?