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Outside experts have heavily criticized the French study, however. Infectious disease geneticist Gaetan Burgio of the Australian National University noted that statistically, weighing national responses to a pandemic on a study of 20 people was unwise, that the French study was not conducted with doctors and patients blind to the treatment, and that only a quarter of the placebo patients had their viral load measured.
Even worse, six patients dropped out of the trial from the group receiving the drug, and three of them ended up in intensive care and one died. These could be viewed as failures of the drug to work against the virus, Alfred Kim of the Washington University Lupus Clinic told Undark magazine. One reason that Trump noted for testing older drugs is that doctors are familiar with their use.
We're not going to have that. But they do have side effects like most drugs, some severe. The scientific literature contains a number of case reports of overdoses , some fatal. Scientists are working hard to confirm the safety of several drugs for this disease.
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This will cause harm and can lead to death. On Monday, an Arizona man in his sixties died after self-medicating with chloroquine phosphate, a drug meant to clean aquariums. Well it finally happened to me. And compounding pharmacies, which can quickly manufacture drugs in capsules and typically step in when shortfalls of manufactured tablets hit, have noticed a run on chloroquine as well. One New York compounding pharmacist, Gopesh Patel, told BuzzFeed News that orders went from around 20 a week to more than a week in the last two months.
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So, supply signals are good. Patel ended the phone call with BuzzFeed News to prepare doses of chloroquine in liquid form for two children, ages 8 and 10, with coronavirus. Why enter a clinical trial, where there is a chance you might not receive an experimental drug if you are in its control arm meant to serve as a comparison with only standard care, when you can just pressure your doctor to give it to you for off-label use?
The University of Minnesota announced the start of a national clinical tria l of hydroxychloroquine early last week, for example, seeking up to 1, people exposed to COVID disease within the past three days, where half of the volunteers would get the drug while the other half receive an identical-looking sugar pill, a placebo.
The University of Minnesota one has an end date of May Even after everything shuts down and the economy tanks, people are still developing the disease, heading to the hospital, and adding to case counts. Trump signals he probably won't just listen to the medical pros: "If it were up to the doctors, they may say, let's keep it shut down.