Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with hydroxychloroquine. Give a list of all your medicines to any healthcare provider who treats you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Avoiding the Traps of Hydroxychloroquine Use
Hydroxychloroquine is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. To prevent malaria: Start taking the medicine 2 weeks before entering an area where malaria is common.
Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. To treat malaria: Hydroxychloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take this medicine for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could cause malaria.
Call your doctor as soon as possible if you have been exposed to malaria, or if you have fever or other symptoms of illness during or after a stay in an area where malaria is common. For best results, keep using the medication as directed. Talk with your doctor if you have fever, vomiting, or diarrhea during your treatment. When treating lupus or arthritis , hydroxychloroquine is usually given daily for several weeks or months.
Hydroxychloroquine (Oral Route) Proper Use - Mayo Clinic
Talk with your doctor if your symptoms do not improve after 6 months of treatment. Seek emergency medical attention or call the Poison Help line at An overdose of hydroxychloroquine can be fatal, especially in children. Hydroxychloroquine overdose must be treated quickly.
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You may be told to induce vomiting right away at home, before transport to an emergency room. Ask the poison control center how to induce vomiting in the case of an overdose.
Keeping an eye out for problems
Overdose symptoms may include drowsiness, vision changes, slow heart rate, chest pain, severe dizziness, seizure convulsions , or shallow breathing. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place.
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Unlike some of the other traditional disease-modifying antirheumatic drugs DMARDs and biologics, it affects the immune response without suppressing the immune system or increasing the risk of infection. Hydroxychloroquine-related eye problems were once considered rare, but better detection methods now show that they occur in about 7 percent of patients. The risk increases with a higher dose and longer therapy. Hydroxychloroquine is dosed according to body weight.
An eye exam is recommended at the start of treatment to detect any existing vision problems; follow-up tests are needed to catch retinal damage in the earliest stages, before symptoms appear. If found later, damage to the eye may be irreversible, even if the medication is stopped. In a separate study, published in Ophthalmology in early , Rebekah Braslow, MD, and colleagues at NorthShore University HealthSystem in Chicago retrospectively reviewed the records of more than rheumatology patients seen by NorthShore ophthalmologists between and About half had been prescribed too much hydroxychloroquine, and dosing errors continued at the same rate even after the AAO issued revised treatment guidelines in Braslow says several things probably account for prescribing errors.
Some of the blame falls on drug manufacturers, who offer only mg pills, which are hard to calibrate to body weight. As Dr.
Changing and conflicting guidelines may also cause some confusion. The AAO guidelines recommended dosing hydroxychloroquine based on ideal body weight — what a patient should weigh for their height.