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- Chloroquine is now a leading experimental treatment for COVID-19.
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Sign up here. The action comes following President Trump's announcement last week of government approval of testing the two drugs. Over the weekend, he expressed his optimism over the possibility of success calling it "one of the biggest game changers in the history of medicine" when combined with antibiotic Azithromycin.
Still, not everyone is convinced, especially after one man in Arizona treated himself with chloroquine and died. Ishan Azzam, chief medical officer for Nevada's Division of Public and Behavioral Health, called the decision "a strong step in protecting patients". In addition, ingesting too much of either drug could be deadly. An Arizona man died and his wife was hospitalized after the two ingested a version of chloroquine phosphate used to treat fish parasites.
The Companies Involved.
Chloroquine is being tested to treat COVID-19 and prevent people from catching it
In the meantime, several drugmakers are stepping up to assist with testing and potential distribution. At this point, there is simply too much uncertainty associated with the virus, the ongoing clinical trials and the potential timeline for getting drugs to market to make any of these stocks anything more than a speculation at this point. Investors should proceed with caution. Do you agree with this take? See more from Benzinga. Benzinga does not provide investment advice. All rights reserved. Sign in Mail Sign in to view your mail.
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Finance Home. Wayne Duggan. When combined with the antibiotic azithromycin, it also reduced the viral load in these patients, he added.
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Azithromycin helps fight lung infections that can come with COVID and may play a role in fighting the virus, Medscape reported. This French study is one small, low-quality study that needs to be replicated on a larger scale. It tested a very small group with no long-term follow up data, and six patients dropped out early and were excluded from the main analysis.
The French goverment is expanding this testing to see if the results hold up.
Americans are searching for one of Africa’s most common prescribed drugs to battle coronavirus
While experts caution against anyone reaching conclusions about the drug's utility in COVID, President Donald Trump has repeatedly touted chloroquine by name as a promising potential treatment. On Thursday, US Food and Drug Administration Commissioner Stephen Hahn said chloroquine and hydroxycholoroquine will be made available to patients under a compassionate-use program as more data is collected.
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Compassionate-use programs are generally for terminally ill patients who have no other treatment options. They allow doctors to give patients treatments that have not proven to be safe and effective.
Chloroquine, Past and Present | In the Pipeline
Hydroxychloroquine isn't a benign drug either. Self-medicating can be fatal. An Arizona man died after deciding to take a non-pharmaceutical version of chloroquine used to clean fish tanks. That includes remdesivir, an antiviral drug being developed by the giant biotech company Gilead Sciences that World Health Organization officials have called "the most promising candidate" for COVID treatment.
He recently analyzed the early evidence for three top drugs being tested for COVID — remdesivir, chloroquine, and Kaletra, an HIV drug sold by AbbVie — and concluded that chloroquine was the most promising candidate. Early reports about chloroquine's effectiveness have also caught the attention of Elon Musk. Repurposed antiviral drugs aren't likely to be cure-alls, but they are the only near-term treatment options.
It will take months, if not years, to determine whether a new drug or vaccine is safe and effective. Vaccines in particular are seen as the gold standard for infectious diseases because they protect people from infections in the first place. But if drugs like chloroquine and remdesivir work, they could bring major relief to healthcare systems around the world that are feeling the weight of a pandemic. In the US, there are widespread concerns about the likelihood that hospitals will run out of beds and ventilators as the virus spreads, forcing doctors into difficult rationing decisions.
That's already happening in Italy.
Remdesivir, given as a day intravenous infusion, could shorten hospital stays and lower ventilator use if it can help patients with serious COVID cases recover faster.